The removable implant maintained adequate cabotegravir levels for several months in a mouse study without the injectable drug’s “long tail.”
An experimental biodegradable implant for pre-exposure prophylaxis (PrEP) could potentially offer protection against HIV for up to a year, according to early study results published in the Journal of Controlled Release. What’s more, drug levels dropped rapidly when the implant was removed, avoiding the “long tail” problem seen with cabotegravir injections.